Two Cases of Gastric Small Cell Carcinoma who survived Over 2 Years after Curative Gastrectomy and Adjuvant Chemotherapy

Hiroshi Nakayama, Yasuhiko Ishida, Yoshinori Munetomo, Kota Mukai, Tadao Ohyama, Takanori Hirayama and Kunio Okajima

Department of Gastroenterol Surgery, Himeji Central Hospital

We reported rare 2 cases of small cell carcinoma of the stomach, accounting for only 0.06-0.2%of all gastric cancer cases. A 63-year-old Japanese man developed gastric cancer (MU, post, cType 3) and underwent total gastrectomy with D2 lymphadenectomy and Roux-en-Y reconstruction {pT3 (SE), PN1, fStage IIIA}. After 1-year oral 5-FU derivative (UFT) adjuvant chemotherapy, he died of multiple liver and lung diseases at 26 months after surgery. A 64-year-old Japanese man had gastric cancer (L, post, cType 2) and underwent D2 distal gastrectomy with Roux-en-Y reconstruction {pT3 (SE), PN2, fStage IIIB}. He received oral 5-FU derivative (TS-1) for 3 years and is alive without recurrence at 46 months after surgery. Extensive gastrectomy with lymphadenectomy followed by long-term adjuvant chemotherapy is a treatment of choice for gastric small cell carcinoma.

Key words
stomach, small cell carcinoma, neuroendocrine neoplasia

Reprint requests
Hiroshi Nakayama Department of Gastroenterological Surgery, Himeji Central Hospital
2-36 Miyake, Shikama-ku, Himeji, 672-8501 Japan

Accepted
June 27, 2007

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