A Case of Esophageal Adenocarcinoma arising from Heterotopic Gastric Mucosa

Shigeo Haruki, Tatsuyuki Kawano, Kagami Nagai, Tetsuro Nishikage, Yasuaki Nakajima, Kenro Kawada, Kazuo Ogiya, Koji Tanaka and Hiroshi Kawachi*

Department of Surgery and Department of Pathology*, Tokyo Medical and Dental University Hospital

Cervical esophageal adenocarcinoma arising from heterotopic gastric mucosa is rare, with only 16 cases reported, to our knowledge, in Japan. A 35-year-old man reporting odynophagia and hematemesis after drinking alcohol and examined in upper gastrointestinal endoscopy was found to have a tumor at the cervical esophagus. Histologically, biopsy specimens indicated adenocarcinoma. Computed tomography showed swelling of cervical and superior mediastinal lymph nodes. He was treated with esophagectomy with right thoracotomy. Histopathological examination of the resected specimen showed papillary adenocarcinoma with invasion to the submucosa and lymph node metastases. Carcinoma was diagnosed as arising from heterotopic gastric mucosa because of its continuity.

Key words
heterotopic gastric mucosa, adenocarcinoma of esophagus, cervical esophageal carcinoma

Reprint requests
Shigeo Haruki Department of Surgery, Tokyo Medical and Dental University Hospital
1-5-45 Yushima, Bunkyo-ku, 113-8519 JAPAN

Accepted
October 29, 2007

To read the PDF file you will need Abobe Reader installed on your computer.