A Case of Intraductal Papillary Mucinous Neoplasm Accompanied by Triple Cancers

Takeshi Nishi, Seiji Yano, Touko Inao, Yoshihide Simojo, Yasuhiko Yokoyama, Yasunari Kawabata, Noriyuki Hirahara, Masayuki Itakura, Akira Yamanoi and Tsuneo Tanaka

Department of Digestive and General Surgery, Shimane University

Intraductal papillary mucinous neoplasm (IPMN) is reported to complicate malignancies disease in 30% of cases and complicate invasive ductal carcinoma of the pancreas too, but is rare in multiple cancers. We report a patient with IPMN accompanied by triple cancers. The 60-year-old woman had been followed for IPMN for 7 years, during which time she underwent a hysterectomy due to uterine corpus cancer at age 56 and bilateral breast-preserving surgery due to bilateral breast cancer at age 60. During radiation therapy after breast cancer surgery, a tumor was found in the pancreas body in abdominal computed tomography. Magnetic resonance cholangiopancreatography and endoscopic retrograde cholangiopancreatography showed the main pancreas duct to be occluded at the body and at the tail to be delated. Cytology of the pancreatic juice was class IV. We diagnosed pancreatic cancer with IPMN and conducted subtotal distal pancreatectomy, without resecting the IPMN, which was considered benign.
Physicians should look for malignant disease in patients with IPMN because cancer complications may adversely affect their prognosis.

Key words
pancreas cancer, IPMN, multiple cancers

Reprint requests
Takeshi Nishi Department of Digestive and General Surgery, Shimane University
89-1 Enya-cho, Izumo, 693-8501 JAPAN

Accepted
January 30, 2008

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