A Case of the Splenic Angiosarcoma with Morphological Change during Follow-Up

Takahiro Akahori, Masayuki Sho, Yoshikazu Tsurui, Shuji Osumi, Tomomi Tamura*, Masahiro Tutumi**, Akitaka Nonomura* and Yoshiyuki Nakajima

Department of Surgery and Department of Diagnostic Pathology*, Nara Medical University
Department of Diagnostic Pathology, Saiseikai Tyuwa Hospital**

We report a rare case of primary splenic angiosarcoma diagnosed after 3.5-year follow-up as splenic hemangioma. A 77-year-old man with a splenic tumor diagnosed as hemangioma was found in abdominal CT to have morphological change and increased tumor size after 3.5 years. Because we suspected malignant transformation, we conducted splenectomy. The pathological tumor diagnosis was splenic angiosarcoma, and our first case of long-term preoperative observation. This case may aid in understanding the natural history of this disease.

Key words
spleen, angiosarcoma, natural history

Reprint requests
Takahiro Akahori Department of Surgery, Nara Medical University
840 Shijo-cho, Kashihara, 634-8522 JAPAN

Accepted
July 23, 2008

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