A Case of Nephrotic Syndrome Cured by Removal of the Advanced Gastric Cancer

Shojirokazunori Ikenaga¹⁾²⁾, Susumu Oishi¹⁾, Shinji Tsutsumi¹⁾²⁾, Norihito Kubo¹⁾, Makoto Nakai¹⁾, Hideki Matsuya¹⁾, Takaaki Yoshizaki¹⁾ and Hiroshi Tateoka¹⁾

Department of Surgery, Odate Municipal City Hospital¹⁾
Department of Surgery, Graduate School of Medicine, Hirosaki University²⁾

The association between malignant disease and nephrotic syndrome has been established. Here in we report a case of advanced gastric cancer with nephrotic syndrome. An 82-year old woman admitted for bilateral pedal edema and general fatigue was diagnosed with advanced gastric cancer with nephrotic syndrome, necessitating distal gastrectomy with D1+α lymph node dissection. Histology showed poorly differentiated adenocarcinoma, T3, N1, H0, P0, CY1, Stage IV, Cur C. Her urinary protein decreased and symptoms of nephrotic syndrome improved 5 days after surgery. Twelve months after surgery, she had no nephrotic syndrome symptoms or signs of recurrent gastric cancer. Concurrently with non curative surgery for advanced gastric cancer, her symptoms of nephrotic syndrome improved, indicating a potential advantage of surgery in such a case.

Key words
advanced gastric cancer, nephrotic syndrome, non curative surgery

Reprint requests
Shojirokazunori Ikenaga Department of Surgery, Graduate School of Medicine, Hirosaki University
5 Zaihu-cho, Hirosaki, 036-8562 JAPAN

Accepted
November 19, 2008

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