Calcifying Fibrous Tumor of the Gastric Wall

Hirotaka Kitamura, Akira Takehara, Masanari Shimada, Hideki Moriyama, Kennichiro Saito, Masahiro Hada, Kazushige Shibahara, Masatoshi Sasaki, Koji Konishi and Yoshinobu Maeda*

Department of Surgery and Department of Pathology*, Toyama Red Cross Hospital

We report a rare case of calcifying fibrous tumor of the gastric wall. A 44-year old woman was seen by a health checkup barium study for an abnormal observation indicating a round defect impinging on the lumen suggesting submucosal gastric tumor at the distal anterior wall. Gastroscopy revealed a 3×3 cm distal anterior bulge with normal overlying mucosa. Computed tomography (CT) indicated a gastric tumor with calcification projecting from the gastric wall excised in laparoscopic gastric wedge resection. On gross examination, the surgical specimen was a firm gray-white mass 30×26×24 mm well-demarcated but unencapsulated. Microscopically it consisted of dense collagenous tissue containing sparse spindle cells, psammomatous calcification, and multifocal lymphoplasmocytic infiltrates. Immunohistochemically, cells were positive for vimentin and negative for CD34, c-kit, α-smooth muscle actin, desmin, S-100, and NSE. The histology was characteristic of a rare calcifying fibrous tumor-only the second, to our knowledge, reported in Japan.

Key words
calcifying fibrous tumor, calcifying fibrous pseudotumor, submucosal tumor

Reprint requests
Hirotaka Kitamura Department of Surgery, Toyama Red Cross Hospital
2-1-58 Ushijimahonnmachi, Toyama, 930-0859 JAPAN

Accepted
May 27, 2009

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