A Case of Primary Anaplastic Carcinoma of the Jejunum

Takahisa Hiramitsu, Shyoji Hashimoto, Kenichi Nakanishi, Eiji Ohnishi, Hisaharu Ohya, Tetsuo Nishi, Takahiro Mase, Jiro Nagata and Shingo Kawasaki

Department of Surgery, Ichinomiya Municipal Hospital

We report a case of undifferentiated cancer of the jejunum. An 88-year-old man with high fever and abdominal pain and found in blood tests to have an inflammation was further found in enhanced abdominal computed tomography (CT) to have a small intestinal tumor with a thickened wall and containing peritoneal fluid. Peritonitis necessitated emergency surgery, showing an intestinal tumor 20 cm from the Treitz ligament on the anal side and adhering to the small intestine 10 cm from the oral side of the Bauhin valve. Turbid peritoneal fluid was found, but no intestinal perforation. The small intestine was resected extensively. Histologically, the tumor was anaplastic carcinoma. Immunohistochemical examination showed the lesion to be positive for CAM5.2 and p63. The patient recovered enough to be discharged, but he died of multiple brain metastases 3 months postoperatively. Anaplastic carcinoma of the jejunum is rare, with only 14 cases of anaplastic carcinoma of the small intestine reported in the Japanese literature.

Key words
anaplastic carcinoma, small intestinal carcinoma

Reprint requests
Takahisa Hiramitsu Department of Surgery, Ichinomiya Municipal Hospital
2-2-22 Bunkyo, Ichinomiya, 491-8558 JAPAN

Accepted
April 22, 2009

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