A Case of Severe Radiation Enteritis caused by Proton Therapy for Hepatocellular Carcinoma

Ryoichi Miyamoto, Masayoshi Yamamoto, Yoshimasa Akashi, Kazuhiko Yanagisawa, Shinji Sugawara* and Nobuhiro Ohkohchi

Department of Gastroenterological Surgery and Department of Radiology*, University of Tsukuba

We report a case of radiation enteritis caused by proton therapy -an effective treatment modality for hepatocellular carcinoma having fewer side effects on neighboring organs than radiation therapy. A 70-year-old man undergoing transcatheter arterial embolization five times for hepatocellular segment 8 carcinoma gradually suffered indreased side effects, so we changed to proton therapy. Half a year later, he suffered anemia and aggravated hematochezia 2 months later. Admitted in an emergency, he was found to have radiation enteritis. Because of the difficulty in control hemorrhage, we conducted colectomy, after which his condition improved. He underwent proton therapy for the new hepatocellular carcinoma leision three times.

Key words
radiation enteritis, proton therapy, surgery

Reprint requests
Masayoshi Yamamoto Department of Gastroenterological Surgery, University of Tsukuba
1-1-1 Tennoudai, Tsukuba, 305-8575 JAPAN

Accepted
May 27, 2009

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