A Case of Synchronous Double Gastric and Rectal Carcinomas Lymphoplasmacytic Lymphoma responding to Preperative Double Filtration Plasmapheresis

Kei Kusama, Harutsugu Sodeyama, Taiichi Machida, Akito Nishio and Shinji Nakata

Departments of Surgery, Nagano Red Cross Hospital

A 71-year-old man with calf edema and shortness of breath admitted for further examination was found to have a IgM-κ monoclonal protein (3,259 mg/dl) in serum and advanced gastric and rectal cancer. The histological diagnosis of bone marrow biopsy specimens was lymphoplasmacytic lymphoma (LPL), necessitating double filtration plasmapheresis preoperatively, followed by total gastrectomy and anterior rectal resection in May 2008. After an uneventful postoperative course and rituximab treatment 2 month after surgery, he attained a partial response. Lymphoplasmacytic lymphoma is comparatively rare and, to the best of our knowledge, no case combined with advanced gastric cancer synchronous with rectal cancer has been reported in the Japanese literature.

Key words
lymphoplasmacytic lymphoma, double filtration plasmapheresis, rituximab

Reprint requests
Kei Kusama Departments of Surgery, Nagano Red Cross Hospital
5-22-1 Wakasato, Nagano, 380-8582 JAPAN

Accepted
June 18, 2009

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