A Surgical Case of Multiple Colon Cancers and Adenomas Associated with Japanese Schistosomiasis

Katsuyuki Hoshina¹⁾²⁾, Akihiro Hosaka¹⁾ and Jun Matsumoto¹⁾

Department of Surgery, Fuchu Metropolitan Hospital¹⁾
First Department of Surgery, The University of Tokyo Hospital²⁾

We report a very rare case of multiple cancer and adenomas of Japanese schistosomiasis (JS) indicating colorectal carcinogenesis of JS infection. A 66-year-old man admitted for abdominal pain had lived in Yamanashi Prefecture, an area endemic for JS. He had suffered liver dysfunction at the age of 10 years diagnosed as JS infection. X-ray imaging showed several niveaus indicating mechanical obstruction. Following ileus-tube decompression, colon fiberscopy showed advanced double cancer and one adenoma of the sigmoid colon and another of the rectosigmoid colon. Biopsy showed many JS ova around the cancer and adenomas. We conducted anterior resection with lymph node dissection. Five days after surgery jaundice appeared and was treated conservatively. Liver biopsy showed many JS ova. Such cases of multiple tumor or liver dysfunction thought to be at high risk for colon and liver cancer should be stringently followed up via colon fiberscopy and ultrasound observation.

Key words
schistosomiasis japonica, multiple colon cancer, fiberscopy

Reprint requests
Katsuyuki Hoshina First Department of Surgery, The University of Tokyo Hospital
7-3-1 Hongo, Bunkyo-ku, 113-8655 JAPAN

Accepted
September 16, 2009

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