A Recurrent Case of Solid-pseudopapillary Neoplasm of the Pancreas after Twenty Years

Naoki Mashita, Katsumi Koshikawa, Kenji Taniguchi, Yoshinari Mochizuki, Hiroyuki Yokoyama, Hiroyuki Suenaga and Kyoko Kuwahara*

Department of Surgery and Department of Pathology*, Komaki Municipal Hospital

A 32-year-old woman diagnosed with a pancreatic tumor 20 years earlier, treated by resection elsewhere and found histopathologically to be a solid-pseudopapillary neoplasm (SPN) of the pancreas, was seen for abdominal pain at the age of 29. Examination showed her to have a pseudo-cyst of the pancreatic head with intraluminal bleeding. At the age of 31, the solid part of the tumor was suspected to have grown and no pancreatic body or tail was detected. Fine-needle aspiration biopsy yielded a diagnosis of SPN, necessitating tumorectomy with duodenal preservation. Histopathology of the resected specimen was compatible with the SPN. The tumor was positive for NSE, vimentin, PgR, and synaptophysin, similar to the tumor removed 2 decades earlier. We diagnosed the case as a local recurrence of the earlier SPN.

Key words
solid pseudopapillary pancreatic neoplasm, recurrence

Reprint requests
Naoki Mashita Department of Surgery, Komaki Municipal Hospital
1-20 Jyobushi, Komaki, 485-8520 JAPAN

Accepted
January 27, 2010

To read the PDF file you will need Abobe Reader installed on your computer.