A Clinicopathologic Study of 11 Adenosquamous Carcinoma of the Esophagus

Kunimoto Nezu, Hoichi Kato, Yuji Tachimori, Hiroshi Watanabe, Masayuki Itabashi¹⁾, Teruyuki Hirota¹⁾, Yuuko Yamauchi¹⁾, Hajime Yamaguchi²⁾

Department of Surgery, National Cancer Center Hospital
Department of Pathology, National Cancer Center Research Institute¹⁾
Department of Internal Medicine, National Cancer Center Hospital²⁾

Eleven cases of adenosquamous carcinoma of the esophagus were studied clinico-pathologically. Seven of them were early esophageal carcinoma. Endoscopic examination of the lesions revealed that seven were elevated, three stenotic and one superficial. Histological examination revealed that the adenocarcinomatous component was of the glandular type in 10 cases and signet ring cell type in one. Ten lesions showed a mixed histological distribution of adenocarcinomatous and squamous carcinomatous components, while one was a collision type of the two components. The prognostic data showed a better prognosis in patients with adenosquamous carcinoma of the esophagus than in those with squamous cell carcinoma, after curative resection with lymph node dissection.

Key words
adenosquamous carcinoma of the esophagus, adenoacanthoma

Reprint requests
Kunimoto Nezu Third Department of Surgery, Nara Medical College
840 Shijo-cho, Kashihara, Nara, 634 JAPAN

Accepted
September 12, 1990

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