Experimental Study on the Effect of an Artificial Arterio-portal Shunt for the Dearterialized Liver after a Major Hepatic Resection

Toshio Nakagohri, Takehide Asano, Takashi Kenmochi, Takesada Goto, Kazuo Enomoto, Kaoru Sakamoto, Kaichi Isono

Second Department of Surgery, Chiba University School of Medicine

The effect of an artificial arterio-portal shunt (A-P shunt) for the dearterialized liver after a major hepatic resection was studied. Mongrel dogs were divided into 2 groups. The hepatic artery and collaterals to the liver were dissected after 40% hepatectomy in the control group. In the A-P shunt group the hepatic artery and collaterals to the liver were dissected and A-P shunt was made between the common hepatic artery and the gastroduodenal vein after 40% hepatectomy. Blood flow to the liver, pressure of the portal vein, O₂ partial pressure of liver tissue and hepatic enzymes were measured, and a hepaplastin test was carried out. Survival rates were also determined. The O₂ partial pressure of liver tissue and pressure of the portal vein were significantly elevated in A-P shunt group, and the group had better liver function and a better suvival rate. A-P shunt is a possible procedure for dearterialized liver after major hepatic resections.

Key words
artificial arterio-portal shunt, arterialization of the portal vein, dearterialized liver, ligation of hepatic artery, hepatectomy

Reprint requests
Toshio Nakagohri Second Department of Surgery, Chiba University School of Medicine
1-8-1 Inohana-cho, Chiba City, 280 JAPAN

Accepted
December 10, 1991

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