A Case of Gastric Cancer with Extensive Liver Metastases which Disappeared Postoperatively by Administreration of MMC, OK-432 and Lentinan

Yoshikazu Suzuki, Shingo Saito, Kazuhide Iwakawa, Naomi Kawata, Hironobu Shinohara, Takashi Funatsu*, Nobuaki Kobayashi**

Department of Surgery and *Department of Internal Medicine, Tsushima Municipal Hospital
**The First Department of Surgery, School of Medicine, Ehime University

A 60-year-old man underwent partial gastrectomy for Stage IV gastric cancer showed a Type 3 and S₂, N₃, P₀, H₃. Before closing the abdominal wall, we administered mitomycin C (MMC) and OK-432 into the peritoneal cavity. Postoperatively he received chemoimmunotherapy consisting of MMC (i.v.), OK-432 (i.d.) and Lentinan (d.i.v.). After these treatments, metastatic liver tumors were not detected by computed tomography (CT) in the fourth postoperative month. The patient has been healthy for 2 years and 5 months with only Krestin prescribed. Now we cannot find any sign of recurrence. According to our review of the Japanese literature, only 6 patients (H₃) who lived for more than 2 years have been reported. From our patient's postoperative course, we think the chemoimmuno-therapy was very effective.

Key words
liver metastasis of gastric cancer, chemoimmunotherapy

Reprint requests
Yoshikazu Suzuki Department of Surgery, Tsusima Municipal Hospital
15 Takata, Tsushima-cho, Kitauwa-gun, Ehime, 783-33 JAPAN

Accepted
December 10, 1991

To read the PDF file you will need Abobe Reader installed on your computer.