A Case Report of Menetrier Disease Associated with Mucosal Bridges

Noriyuki Okada, Kouji Hanaki, Syuji Kimoto, Yoshiya Kawaguchi, Kazuyuki Kawamoto, Katsuhiro Asonuma, Tadashi Ito, Yasuo Yashida, Eiji Kii, Yukihiro Kono, Keizo Ogasahara, Hidenari Takasan

Department of Surgery, Kurashiki Central Hospital

A case of hypertrophic gastritis with superficial multiple ulcers and mucosal bridges is reported. A 74-year-old woman was admitted to our hospital because of vomiting and malnutrition. Upper gastrointestinal X-ray study and gastric endoscopy revealed a thickened, irregular gastric wall and pooling of a barium meal which looked like a diverticulum. We could not rule out scirrhous cancer, and a total gastrectomy was performed. The resected specimen showed multiple ulcers and mucosal brides among giant rugae on the greater curvature. Histologically, the mucosa of the bridge consisted of fundic glands, and the bottom mucosa showed scars or pyloric glands. It is likely that ulcers penetrating through the gastric mucosa caused mucosal bridge formation. In the literature, the mucosal bridge of the stomach is reported less often than that of the large intestine. Only 12 cases of gastric mucosal bridge have been reported in Japan.

Key words
mucosal bridge, Menetrier disease, hypertrophic gastritis

Reprint requests
Noriyuki Okada Department of Surgery, Kurashiki Central Hospital
1-1-1 Miwa-cho, Kurashiki-city, 710 JAPAN

Accepted
June 17, 1992

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