A Case of Recklinghausen's Disease Accompanied with Pancreatitis

Ryo Yoshida, Yoshinori Hamada, Hideho Takada, Yasunori Katou, Tsuyoshi Mori, Munehisa Kogata, Kyouji Nakane, Koshiro Hioki

Second Department of Surgery, Kansai Medical University

Neurofibroma was first described by von Recklinghause, and this disease usually involves the skin, subcutaneous tissue and bone. We report an extremely rare case of pancreatitis due to neurofibroma of the duodnum caused by von Recklinghausen's disease. The patient was a 59-year-old man who had a past history of von Recklinghausen's disease. He was referred to our hospital with a diagnosis of pancreatitis. CT, MRI, ERCP and angiography suggested a benign tumor of the head of the pancreas. Pancreaticoduodenectomy with preservation of the pylorus was performed. The tumor measured 1 cm in diamter, and was diagnosed as neurofibroma of the duodenum. The tumor cells showed immunoreactivity with anti-s-100 antibody.

Key words
duodenal neurofibroma, von Recklinghausen's disease, pancreatitis

Reprint requests
Ryo Yoshida Second Department of Surgery, Kansai Medical University
10-15 Fumizonocho, Moriguchi, 570 JAPAN

Accepted
December 6, 1995

To read the PDF file you will need Abobe Reader installed on your computer.