A Case of Anal Canal Cancer with Perianal Pagetoid Spread

Fumie Ihara, Kazuo Ueda^*, Naoki Shirohara^*, Hiroko Nonaka, Michio Akima and Tadaaki Shiba^*

First Department of Pathology, Toho University School of Medicine ^*Second Department of Surgery, Toho University School of Medicine

A 68-year-old man consulting a physician, about anal bleeding was diagnosed with an anal canal tumor and visited our hospital. A white discolored area was seen at the perianal skin and was transanally excised at the patient's request. The 2×1.5 cm tumor was histologically as mucinous adenocarcinoma infiltrating the muscular propria and accompanied by perianal pagetoid spread. The man underwent abdominoperineal resection with complete resection of the pagetoid lesion in the perianal skin. Discrete, well- differentiated intramucosal adenocarcinoma was recognized in the rectum. Cancer of anal canal is rarely accompanied by pagetoid spread and only 30 cases have been reported to our knowledge. The patient is well with no evidence of recurrence 3 years and 2 months after operation.

Key words
anal canal cancer, pagetoid spread

Reprint requests
Fumie Ihara First Department of Pathology, Toho University School of Medicine 5-21-16 Ohmorinishi, Ohta-ku, Tokyo, 143-8540 JAPAN

Accepted
January 31, 2001

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