A Case of Giant Gastrointestinal Stromal Tumor of the Greater Omentum

Kazunori Shimada, Noritsugu Ogawa, Shin Mizutani and Yasushi Tanaka

Department of Surgery, Ashiya Municipal Hospital

A 78-year-old man noting an abdominal mass about 6 months earlier was admitted for abdominal distention and dyspnea with a giant abdominal mass and necrotic umbilicus on August 31,2001. Contrast-enhanced abdominal computed tomography (CT) showed a 30×25 cm mass occupying the whole abdomen, consisting of heterogeneously enhanced solid and giant cystic lesions. The origin of the tumor was unclear. Distant metastasis was not found, so laparotomy was done and the noninvasive tumor found to have arisen in the greater omentum. The resected tumor was 30×25×10 cm in diameter and weighed 3,854 g. Histologically, the tumor was consisted of proliferated spindle cells or epithelioid cells with irregular and fascicular patterns and mitotic figures in a 4∼5/10 high power field. Immunohistochemically, tumor cells were positive for c-kit and partially positive for CD34, indicating gastrointestinal stromal tumor (GIST) of the greater omentum. The man remains alive and recurrence-free 11 months after resection.

Key words
gastrointestinal stromal tumor of the greater omentum, giant tumor, c-kit

Reprint requests
Kazunori Shimada Department of Surgery, Ehime National Hospital 366 Yokogawara, Shigenobu-machi, Onsen-gun, Ehime 791-0281 JAPAN

Accepted
February 26, 2003

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