A Case Report of Adenomatoid Tumor of the Adrenal Gland Mimicking an Adrenal Metastasis from Sigmoid Colon Cancer

Akio Shiomi, Yusuke Kinugasa, Syuji Saito, Yousuke Hashimoto, Hiroyuki Tomioka, Katsuhiko Uesaka¹⁾, Masanori Terashima¹⁾, Kouiku Asakura²⁾ and Keiko Sasaki³⁾

Division of Colorectal Surgery, Division of Surgery¹⁾, Division of Radiology²⁾ and Division of Pathology³⁾, Shizuoka Cancer Center Hospital

Adenomatoid tumors (AT) of the adrenal gland are rare, benign, asymptomatic neoplasms usually found incidentally. We report a 65-year-old man diagnosed with an adenomatoid tumor of the adrenal gland mimicking adrenal metastasis from sigmoid colon cancer. The man was originally diagnosed with sigmoid colon cancer with a simultaneous left adrenal solid tumor 3 cm in diameter in preoperative imaging. The tumor was gradually enhanced on dynamic computed tomography (CT). The tumor showed isointensity on T1WI and T2WI in magnetic resonance imaging (MRI), and showed abnormal FDG uptake in PET/CT. We diagnosed sigmoid colon cancer and simultaneous adrenal metastasis preoperatively, conducting sigmoidectomy with lymphadenectomy and left adrenalectomy. Histologically, the tumor had the typical appearance of AT of the genital tract. Immunohistochemically, tumor cells were positive for calretinin, AE1/AE3, and vimentin and negative for endothelial markers CD31, D2-40, and S-100 protein, confirming AT of the adrenal gland a very rare tumor for which only 28 cases have been reported in the English literature.

Key words
adenomatoid tumor, adrenal metastasis, colon cancer

Reprint requests
Akio Shiomi Division of Colorectal Surgery, Shizuoka Cancer Center Hospital
1007 Shimonagakubo, Nagaizumi, Sunto, 411-8777 JAPAN

Accepted
September 16, 2009

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